COVID-19 is an emerging, rapidly evolving situation. We supply many industries on a global basis. 89399-28-0. Dipropylene Glycol Butyl Ether is the propylene oxide-based glycol ether. Cancer . In the 2-year study, male rats displayed exposure-related nonneoplastic lesions in the kidney, and may have shown marginal increases in tubular neoplasms. The EPA requires It is used in a variety of coating, printing ink, and cleaning applications. For example, propylene glycol ethyl ether (PGEE) and its acetate do not cause the critical toxicities of testicular, thymic, or blood injury and do not produce birth defects. It is majorly used in products that are used in treating metal and non-metal surfaces, laboratory products, and in water treatment formulation. The PPG stands for propylene glycol. Propylenglycolmonobutylether wird als Lösungsmittel und Insektenvertreibungsmittel verwendet.. Sicherheitshinweise. Propylene glycol tertiary ‐butyl ether (PGTBE) also has been tested and fails to cause these toxicities or birth defects in rats exposed by inhalation to substantial concentrations. With outstanding soil removal and coupling properties, it takes the lead as Dow’s most hydrophobic glycol ether … The PPG stands for propylene glycol. MDL number MFCD01781688. Let us know if there’s something you want, but don’t see listed. Dipropylene Glycol Butyl Ether is manufactured by reacting Propylene Oxide with Butanol. This site needs JavaScript to work properly. Below our list and specifications of propylene glycol ethers. (Mono) Propylene Glycol Normal Butyl Ether – is a colorless combustible liquid with an ether-like odor. Glycols are rarely found in nature but the simple structure especially of propylene glycols (i.e. Butyl Polyoxyalkylene Ethers (new data only) – Dec 2016 – Monice Fiume Reported Use - … Occupational diseases associated with exposure to this agent: Industrial Processes with risk of exposure: Butoxypropanol; 1,2-Propylene glycol 1-monobutyl ether; 1-Butoxy-2-propanol; 2-Hydroxy-3-butoxypropane; Propasol solvent B; Propylene glycol monobutyl ether; n-Butoxy-2-propanol; n-Butoxypropanol; 1-Butoxypropan-2-ol; 2-Propanol, 1-butoxy-; [ChemIDplus] PnB; [Reference #1] Dowanol PNB glycol ether; [Dow Chemical MSDS] PGBE; [Glycol Ethers Online], Colorless liquid; [ICSC] Odor of ether; [Dow Chemical MSDS], Propylene series glycol ethers are used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks; [ECETOC] Used as a coupling agent and solvent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), coupling agent (water-based agricultural formulations), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers); [Reference #1], Adverse effects in animal studies include adaptive liver changes and reversible CNS depression, but no hematological, genotoxic, or carcinogenic effects; [ToxPlanet: ECETOC] A skin and eye irritant; [ICSC] May cause moderate skin and eye irritation; May cause mild, reversible corneal injury; [Dow Chemical MSDS] See "Dipropylene glycol n-butyl ether.". eCollection 2018 Mar. Regul Toxicol Pharmacol. Doi AM, Hill G, Seely J, Hailey JR, Kissling G, Bucher JR. Toxicol Pathol. Crit Rev Toxicol. propylene glycol monobutyl ether . EC Number 249-951-5. Renal lesions suggestive of alpha(2u)-globulin nephropathy were observed in male F344/N, in the 2 and 14-week studies, no kidney lesions were seen in NBR rats. Toxicol Sci. C&L Inventory . 1,2'-oxydipropanol dimethyl ether PnP Glycol Ether Propylene Glycol n-Propyl Ether NO 1.5 0.21 118/48 25.4 15.3 4.9 11.2 ∞ Applications Air fresheners and fragrances, cleaner formulations such as glass cleaners, hard surface cleaners, floor cleaners, rust removers, industrial cleaners, and metal cleaners DOWANOL™ TPnB Glycol Ether Tripropylene Glycol n-Butyl Ether Other uses and applications for PGEs include agricultural, cosmetic, electronic, ink, textile and adhesive products. About 2% of these are Alcohol & Hydroxybenzene & Ether. used as a PENETRATION enhancer. Developmental & Reproductive Toxicity . No Data, Some Concern . No Data, Some Concern . 1-Butoxy-2-propanol . 1,2- and more so 1,3-propanediol) makes it very likely (I have to admit, I do not know for certain but think that it actually is the case) that these do indeed occur as side products in trace amounts for example in natural microbial metabolism. Propylene glycol mono n-butyl ether . Propylene glycol butyl ether ≥99% Synonym: DOWANOL ® PnB CAS Number 5131-66-8. Propylene glycol mono-t-butyl ether; Propylene glycol mono-t-butyl ether . Please contact us with questions or to… 2004 Nov 15;204(2-3):123-40. doi: 10.1016/j.tox.2004.06.019. In glycols, the alcohol groups are attached to different carbons. Environ Health Perspect. It has low water solubility and good coupling and demonstrates good solvency for coating resins. Alpha 2u-globulin nephropathy and carcinogenicity following exposure to decalin (decahydronaphthalene) in F344/N rats. Belongs to the Following Reactive Group(s) It evaporates slowly and does not mix well with water. PROPYLENE GLYCOL T-BUTYL ETHER is incompatible with acids, oxidizing agents, oxygen (prolonged contact), water and dehydrating agents. Dipropylene glycol dimethyl ether. PnP is a propylene oxide-based, or Pseries, glycol ether. 2018 Jul 1;198(1):67-76. doi: 10.1164/rccm.201710-2033OC. CAS Number 1928-45-6 Synonym(s) Dow Weed Killer X; 2,4-D PGBE; Caswell No. Now question is, what does 1,3-Propenediol metabolize to? Dipropylene Glycol Butyl Ether is supplied as a product that is >98.5% pure. Basis for Listing AB-NTP. Dipropylene glycol monomethyl ether (also known as Methoxy Propoxy Propanol, Oxybispropanol, dipropylene glycol methyl ether, DPM, and Dowanol DPM) is a propylene oxide-based/P series glycol ether and has the formula C 7 H 16 O 3.It is a clear, colourless, viscous liquid which has a slight ether … Glycols & Glycol Ethers FBC offers a wide variety of Gycols and Gycol Ethers commonly used in cleaner and paint formulations. Propylene Glycol N-Butyl Ether is a solvent that can be found in common household kitchen cleaners. It evaporates quickly and is completely soluble (mixes easily) in water. A colorless liquid with an ether-like odor. (NTP, 1992). May initiate the polymerization of isocyanates and epoxides. Registration dossier . 2007 Jun;35(4):533-40. doi: 10.1080/01926230701338941. Propylene glycol mono--butyl ether is used as a solvent in all-purpose cleaners, inks, and nail polish lacquers. The kidney and the liver were targets of PGMBE toxicity in rats. It is found in antifreeze, most. For example, propylene glycol ethyl ether (PGEE) and its acetate do not cause the critical toxicities of testicular, thymic, or blood injury and do not produce birth defects. LyondellBasell offers a broad line of glycol ethers based on ethylene and propylene. ether? Dipropylene Glycol Butyl Ether is supplied as a product that is >98.5% pure. C&L Inventory . Dipropylene Glycol Butyl Ether is manufactured by reacting Propylene Oxide with Butanol. A colorless liquid with an ether-like odor. Trade names . It is used as stabilizer for vitamins, and as a water-miscible cosolvent. Male and female F344/N rats and B6C3F(1) mice were exposed to PGMBE by whole-body inhalation for 2 or 14 weeks (0, 75, 150, 300, 600, or 1200 ppm) or 2 years (0, 75, 300, or 1200 ppm); male NBR rats were exposed for 2 weeks. What’s so bad about PPG-14 butyl. Supplier A wide variety of di propylene glycol butyl ether options are available to you, such as classification, grade standard, and type. These compounds are alkyl ethers which originate from either ethylene glycol (“E-series”) or propylene glycol (“P-series”). Distributed for comment only -- do not cite or quote . 2003 Apr;72(2):223-34. doi: 10.1093/toxsci/kfg028. PnP is commercially available as a mix of two isomers. Clipboard, Search History, and several other advanced features are temporarily unavailable. Epub 2008 Oct 5. Evaluation of e-liquid toxicity using an open-source high-throughput screening assay. 2004 Mar;(515):1-306. Ghosh A, Coakley RC, Mascenik T, Rowell TR, Davis ES, Rogers K, Webster MJ, Dang H, Herring LE, Sassano MF, Livraghi-Butrico A, Van Buren SK, Graves LM, Herman MA, Randell SH, Alexis NE, Tarran R. Am J Respir Crit Care Med. 57018-52-7) in F344/N rats and B6C3F1 mice and a toxicology study of propylene glycol mono-t-butyl ether in male NBR rats (inhalation studies). Propylenglycolmonobutylether ist eine farblose Flüssigkeit mit etherischem Geruch, die löslich in Wasser ist. Registration dossier . Cogliano VJ, Grosse Y, Baan RA, Straif K, Secretan MB, El Ghissassi F; Working Group for Volume 88. 2018 Mar 27;16(3):e2003904. P-Series glycol ethers are propylene oxide-based, more hydrophobic, have lower surface tension and lower toxicity, and work well in higher pH systems. Listed as Causing Cancer. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Toxicology and Carcinogenesis Studies of Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol Mono-t-Butyl Ether In Male NBR Rats (Inhalation Studies) For example, propylene glycol ethyl ether (PGEE) and its acetate do not cause the critical toxicities of testicular, thymic, or blood injury and do not produce birth defects. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. Propylene Glycol is. Please enable it to take advantage of the complete set of features! used as a PENETRATION enhancer. Natl Toxicol Program Tech Rep Ser. This substance ranges from B to C depending on concentration/usage. Effective coupling agent and efficient solvent for water-reducible coatings. NACRES NA.23 2009 Feb;53(1):6-15. doi: 10.1016/j.yrtph.2008.09.005. Male and female F344/N rats and B6C3F (1) mice were exposed to PGMBE by whole-body inhalation for 2 or 14 weeks (0, 75, 150, 300, 600, or 1200 ppm) or 2 years (0, 75, 300, or 1200 ppm); male NBR rats were exposed for 2 weeks. Propylene Glycol N-Butyl Ether Definition. • Ethylene glycol monomethyl ether (2-methoxyethanol, CH3OCH2CH2OH) Ethoxydiglycol, the ethyl ether of diethylene glycol, contains only one hydroxyl group. In the 2-year study, the incidences of exposure-related hepatocellular adenoma, adenoma or carcinoma combined, and hepatoblastoma occurred with a positive trend, and were significantly increased in 1200 ppm groups. It is a mixture of four isomers. 2007 May;37(4):287-312. doi: 10.1080/10408440601177723. It is so toxic, and penetrates so quickly that. Other Applications: The properties listed in the previous section also support the use of Glycol Ether PNB in agriculture, cosmetics, electronics, ink, textile and adhesive products. EC Number 225-878-4. Propylene Glycol Butyl Ether is the propylene glycol ether of n-butyl alcohol that conforms to the formula: C 7 H 16 O 2 Propylene Glycol is. Propylene glycol mono-t-butyl ether (PGMBE) is used as a solvent in a variety of commercial applications. Belongs to the Following Reactive Group(s) Propylene glycol tertiary‐butyl ether (PGTBE) also has been tested and fails to elicit these toxicities or birth defects in rats exposed by inhalation to substantial concentrations. Propylene glycol (1, 2-propanediol) is an organic compound (a diol alcohol) and is a tasteless, odorless and colorless clear oily liquid. Propylene Glycol n-Butyl Ether (PnB) CAS# 5131-66-8 Description Poly-Solv PnB - Propylene Glycol n-Butyl Ether is a clear, colorless liquid having a mild characteristic odor. 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